| CatalogCode: | NB120-16670 |
| ProductName: | ALK Antibody |
| Product Description: | Rabbit Monoclonal anti-ALK (SP8) |
| Clone: | SP8 |
| Clonality: | Monoclonal |
| Immunogen: | Recombinant protein corresponding to a region which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript. |
| CrossReactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.5 ml |
| Uses: | IHC-P: 1/100. Staining of formalin-fixed tissues is required by boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cell Membrane |
| Control: | Anaplastic lymphoma |
| Background: | This antibody recognises a human p80 protein, identified as a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in a third of large cell lymphomas. This rabbit polyclonal antibody can be used to detect p80 in these lymphomas and may also be used to detect a recently described subtype of large B cell lymphoma, which expresses the full-length ALK protein. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Tissue culture supernatant |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Preservative: 0.1% Sodium Azide |
| ListPrice: | 330 |
| AppSummary: | IHC-P |
| SpeciesSummary: | Hu |
| ProteinTarget: | ALK |
| PackageSize: | 0.5 ml |