| CatalogCode: | NB120-16660 |
| ProductName: | Estrogen Receptor Antibody |
| Product Description: | Rabbit Monoclonal anti-Estrogen Receptor (SP1) |
| Clone: | SP1 |
| Clonality: | Monoclonal |
| Immunogen: | Synthetic peptide (Human) (C terminal). |
| Epitope: | C-terminal |
| CrossReactivity: | Cross-reacts with Human, Mouse, Rat and Hamster.Not yet tested in other species. |
| Packaging: | 0.5 ml |
| Uses: | IHC-P: 1/100. Staining of formalin-fixed tissues is required by boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. WB: 1/200. Predicted molecular weight: 67 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Nuclear |
| Background: | ER content of breast cancer tissue is an important parameter in the prediction of prognosis and response to endocrine therapy. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Tissue culture supernatant |
| Isotype: | n/a |
| Host_Name: | Rabbit |
| Buffer: | Preservative: 0.1% Sodium Azide |
| ListPrice: | 330 |
| AppSummary: | IHC-P, WB |
| ALTnames: | anti-DKFZp686N23123 antibody, anti-ER alpha antibody, anti-ER antibody, anti-Era antibody, anti-ESR 1 antibody, anti-ESR antibody, anti-ESR1 antibody, anti-ESRA antibody, anti-Estradiol receptor antibody, anti-Estrogen receptor 1 antibody, anti-Estrogen receptor antibody, anti-Major ORF antibody, anti-NR3A1 antibody |
| ProteinTarget: | Estrogen Receptor |
| PackageSize: | 0.5 ml |
| GeneralRef: | This clone has been used in:Huang Z et al. Development of new rabbit monoclonal antibody to estrogen receptor (clone SP1): Immunohistochemical assessment on formalin fixed,paraffin-embedded tissue sections. Appl Immunohistochem Mol Morphol : (2005).Cano G et al. Estimation of hormone receptor status in fine-needle aspirates and paraffin-embedded sections from breast cancer using the novel rabbit monoclonal antibodies SP1 and SP2. Diagn Cytopathol 29:207-11 (2003). |
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