| CatalogCode: | NB120-15314 |
| ProductName: | GSK3 Antibody |
| Product Description: | Rabbit Polyclonal anti-GSK3 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide (Human) (C terminal). |
| CrossReactivity: | Cross-reacts with Human, Mouse, Rat, Chicken and Monkey.Not yet tested in other species. |
| Packaging: | 0.5 ml |
| Uses: | IHC-P: Use at a dilution of 1/100 for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate, pH 6.0 for 10 min followed by cooling at RT for 20 min. WB: Use at an assay dependent dilution. Predicted molecular weight: 52 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Control: | Jurkat cells and brain |
| Background: | GSK3 (Glycogen Synthase Kinase-3 differs from most serine/threonine kinases) in that it is active in the absence of the action of signaling pathways. Two isoforms exist, GSK-3a and GSK-3ß. The function of GSK-3 is to phosphorylate glycogen synthase and thereby inactivate it. Insulin action stimulates the PI 3-kinase pathway, resulting in Akt activation, which phosphorylates and inactivates GSK-3. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Preservative: Sodium AzideConstituents: BSA, 10mM PBS. pH 7.4 |
| ListPrice: | 330 |
| AppSummary: | IHC-P, WB |
| ProteinTarget: | GSK3 (alpha + beta) |
| PackageSize: | 0.5 ml |
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