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| Catalog Code: | NB120-15313 |
| Product Name: | Granzyme B Antibody |
| Product Description: | Rabbit Polyclonal anti-Granzyme B |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Immunogen: | Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (N terminal). |
| Cross Reactivity: | Cross-reacts with Human, Mouse and Rat.Not yet tested in other species. |
| Packaging: | 0.05 mg Immunogen affinity purified Rabbit antisera. |
| Uses: | Immunohistochemistry-Paraffin Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. |
| Localization: | Cytoplasmic granules of cytolytic T-Lymphocytes |
| Background: | Granzyme B is a cysteine protease found in the cytoplasmic lysosome-like granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells and is is required for the induction of target cell lysis. This occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Application Summary: | immunohistochemistry assay dependent, Immunohistochemistry-Paraffin assay dependent |
| Species Summary: | Hu, Mu, Rt, |
| Alternate Names: | anti-C11 antibody, anti-Cathespin G Like 1 antibody, anti-CCPI antibody, anti-CGL 1 antibody, anti-CGL1 antibody, anti-CSP B antibody, anti-CSPB antibody, anti-CTLA 1 antibody, anti-CTLA1 antibody, anti-CTSGL 1 antibody, anti-CTSGL1 antibody, anti-Cytotoxic serine protease B antibody, anti-Cytotoxic T Lymphocyte Associated Serine Esterase 1 antibody, anti-Cytotoxic T lymphocyte proteinase 2 antibody, anti-EC 3.4.21.79 antibody, anti-Fragmentin 2 antibody, anti-Fragmentin2 antibody, anti-Granzyme 2 antibody, anti-Granzyme2 antibody, anti-GranzymeB antibody, anti-GRB antibody, anti-GZMB antibody, anti-HLP antibody, anti-Human lymphocyte protein antibody, anti-Lymphocyte protease antibody, anti-Protease Serine B antibody, anti-SECT antibody, anti-T cell serine protease 1 3E antibody |
| Package Size: | 0.05 mg |
| Preservative: | Sodium Azide |
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more information: | company product webpage |
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