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| Catalog Code: | NB120-15252 |
| Product Name: | Wnt1 Antibody |
| Product Description: | Rabbit Polyclonal anti-Wnt1 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Immunogen: | Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (N terminal). |
| Cross Reactivity: | Cross-reacts with Human, Mouse and Rat.Not yet tested in other species. |
| Packaging: | 7 ml Immunogen affinity purified Rabbit IgG. |
| Uses: | IHC-P: Use neat for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Possibly secreted and associates with the extracellular matrix. |
| Background: | Wnt1 is a secreted protein that signals through the Frizzled family of cell surface receptors and is required for normal embryonic development. Wnt1 activation induces a complex signaling cascade that ultimately leads to the increased expression of over fifty genes. An important component of Wnt1 signaling is the stabilization, and resulting accumulation, of the intracellular signaling protein, beta catenine. Mature human Wnt1 is a glycosylated protein containing 343 amino acid residues. Elevated levels of Wnt proteins are associated with tumorigenesis and are present in numerous human breast cancers. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | PBS and BSA |
| Application Summary: | immunohistochemistry-P |
| Species Summary: | Hu, Mu, Rt, |
| Alternate Names: | anti-NT 1 antibody, anti-INT1 antibody, anti-Murine mammary tumor virus integration site 1 antibody, anti-Oncogene INT1 antibody, anti-Proto oncogene protein Wnt 1 antibody, anti-Wingless type MMTV integration site family member 1 antibody, anti-Wnt 1 antibody, anti-Wnt1 proto oncogene protein precursor antibody |
| Package Size: | 7 ml |
| Preservative: | 0.05% NaN3 |
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more information: | company product webpage |