| CatalogCode: | | NB120-15183 |
| ProductName: | | Bcl2 Antibody |
| Product Description: | | Mouse Monoclonal anti-Bcl2 (SPM117) |
| Clone: | | SPM117 |
| Clonality: | | Monoclonal |
| Immunogen: | | Synthetic peptide: GAAPAPGIFS SQPG, corresponding to amino acids 41-54 of Human Bcl2. |
| CrossReactivity: | | Cross-reacts with Human. Does not cross-react with Mouse or Rat. Not yet tested in other species. |
| Packaging: | | 7 ml protein G purified Mouse IgG. |
| Uses: | | IHC-P: Ready to use. Perform enzymatic antigen retrieval before commencing with IHC staining protocol, by boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | | Endoplasmic reticulum, Outer Mitochondrial membrane and Nuclear membrane |
| Control: | | Tonsil |
| Background: | | Bcl2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of Bcl2, such as in the case of translocation of Bcl2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C terminal ends. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | | protein G purified |
| Isotype: | | IgG1 |
| Host_Name: | | Mouse |
| Buffer: | | prediluted antibody |
| ListPrice: | | 285 |
| AppSummary: | | IHC-P |
| SpeciesSummary: | | Hu, Mu(-), Rt(-) |
| ALTnames: | | anti-Apoptosis regulator Bcl 2 antibody, anti-Apoptosis regulator Bcl2 alpha antibody, anti-Apoptosis regulator Bcl2 antibody, anti-B cell CLL alpha / lymphoma 2 alpha antibody, anti-B cell CLL/lymphoma 2 antibody, anti-B cell leukemia alpha / lymphoma 2 alpha antibody, anti-B cell leukemia/lymphoma 2 antibody, anti-B cell lymphoma 2 alpha antibody, anti-B cell lymphoma 2 antibody, anti-Bcl 2 antibody, anti-Bcl2 antibody, anti-BCL2 protein antibody |
| ProteinTarget: | | Bcl2 prediluted |
| PackageSize: | | 7 ml |
| more information: | | company product webpage |
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