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| Catalog Code: | NB120-15128 |
| Product Name: | Amylin Antibody |
| Product Description: | Rabbit Polyclonal anti-Amylin |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Immunogen: | Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (N terminal). |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 7 ml Immunogen affinity purified Rabbit IgG. |
| Uses: | IHC-P: Use neat for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min before commencing with staining protocol.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cytoplasmic and Secreted |
| Background: | Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | PBS, BSA |
| Application Summary: | immunohistochemistry-P |
| Species Summary: | Hu, |
| Alternate Names: | anti-DAP antibody, anti-Diabetes associated peptide antibody, anti-IAP antibody, anti-IAPP antibody, anti-Insulinoma amyloid peptide antibody, anti-islet amyloid polypeptide antibody |
| Package Size: | 7 ml |
| Preservative: | Sodium Azide |
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more information: | company product webpage |