| Catalog Code: | NB120-14309 |
| Product Type: | Primary Antibody |
| Product Name: | Lamin A - Nuclear Envelope Marker Antibody |
| List Price: | 330 |
| Clonality: | Polyclonal |
| Gene ID: | 25777 |
| Host: | Chicken |
| Isotype: | IgY |
| Product Description: | Chicken Polyclonal anti-Lamin A - Nuclear Envelope Marker - Nuclear Envelope Marker |
| Cross Reactivity: | Cross-reacts with Mouse, Rat and Human.Expected to cross-react with Zebrafish (89% identity with immunogen), Chicken (93% identity with immunogen) and Xenopus laevis (87% identity with immunogen) due to sequence homology.Not yet tested in other species. |
| Species Summary: | Hu, Mu, Rt |
| Immunogen: | Synthetic peptide: TESEEVV SREVSGIKAA YEAELGDARK TLDSVAKERA RLQLELSKVR EEFKELKARN TK, corresponding to amino acids 64-122 of Lamin A. |
| Localization: | Nuclear membrane |
| Purity: | Immunogen affinity purified |
| Buffer: | Preservative: NoneConstituents: PBS |
| Packaging: | 50 micrograms |
| Package Size: | 0.05 mg |
| Concentration: | 1 mg/ml |
| Uses: | IHC: Use at a dilution of 1/200. WB: Use at a dilution of 1/2000. Predicted molecular weight: 74 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Application Summary: | IHC, WB |
| General References: | General / background references:Fatkin D et al. Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease. N Engl J Med 341:1715-24 (1999). |
| Notes Main: | During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 uL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tableto |