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| Catalog Code: | NB120-14254 |
| Product Name: | POLR2L Antibody |
| Product Description: | Chicken Polyclonal anti-POLR2L |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | Full length protein. |
| Cross Reactivity: | Cross-reacts with Human and Mouse.Not yet tested in other species. |
| Packaging: | 0.05 mg Immunogen affinity purified Chicken IgY. |
| Uses: | IHC: Use at a dilution of 1/500. WB: Use at a dilution of 1/2000. Predicted molecular weight: 7.6 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Nuclear |
| Background: | This protein is a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. It contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgY |
| Host Name: | Chicken |
| Buffer: | PBS |
| Application Summary: | immunohistochemistry, Western Blot |
| Species Summary: | Hu, Mu, |
| Alternate Names: | anti-DNA directed RNA polymerase II polypeptide L antibody, anti-hRPB7.6 antibody, anti-hsRPB10b antibody, anti-RNA polymerase II polypeptide L antibody, anti-RPABC5 antibody, anti-RPB10 antibody, anti-RPB10beta antibody, anti-RPB7.6 antibody |
| Package Size: | 0.05 mg |
| Preservative: | none |
| Notes Main: | During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 uL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap. |
| General References: | General / background references:Cramer P et al. Architecture of RNA polymerase II and implications for the transcription mechanism. Science 288:640-9 (2000). |
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more information: | company product webpage |