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| Catalog Code: | NB120-14252 |
| Product Name: | POLR2C Antibody |
| Product Description: | Chicken Polyclonal anti-POLR2C |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | Full length protein. |
| Cross Reactivity: | Cross-reacts with Human, Mouse and Rat.Not yet tested in other species. |
| Packaging: | 0.05 mg Immunogen affinity purified Chicken IgY. |
| Uses: | IHC: Use at a dilution of 1/500. WB: Use at a dilution of 1/1000. Predicted molecular weight: 33 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Nuclear |
| Background: | This protein is the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. It contains a cysteine rich region and exists as a heterodimer with another polymerase subunit. These two subunits form a core subassembly unit of the polymerase. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgY |
| Host Name: | Chicken |
| Buffer: | PBS |
| Application Summary: | immunohistochemistry, Western Blot |
| Species Summary: | Hu, Mu, Rt, |
| Alternate Names: | anti-RNA polymerase II polypeptide C antibody, anti-RNA polymerase II subunit 3 antibody, anti-RPB3 antibody |
| Package Size: | 0.05 mg |
| Preservative: | none |
| Notes Main: | During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 uL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap. |
| General References: | General / background references:Fanciulli M et al. The interacting RNA polymerase II subunits, hRPB11 and hRPB3, are coordinately expressed in adult human tissues and down-regulated by doxorubicin. FEBS Lett 427:236-40 (1998). |
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more information: | company product webpage |