| CatalogCode: | NB120-14240 |
| ProductName: | Cdc25C2 Antibody |
| Product Description: | Chicken Polyclonal anti-Cdc25C2 |
| Clonality: | Polyclonal |
| Immunogen: | Recombinant fragment, corresponding to amino acids 351-400 of Human CDC25C2. |
| CrossReactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.05 mg Immunogen affinity purified Chicken IgY. |
| Uses: | ICC: Use at a dilution of 1/200. WB: Use at a dilution of 1/500. Predicted molecular weight: 53 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Nuclear |
| Background: | Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgY |
| Host_Name: | Chicken |
| Buffer: | PBS |
| ListPrice: | 285 |
| AppSummary: | ICC, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-CDC 25 antibody, anti-Cdc 25C antibody, anti-CDC25 antibody, anti-Cell division cycle 25 homolog C antibody, anti-Cell division cycle 25C antibody, anti-Cell division cycle 25C protein antibody, anti-Dual specificity phosphatase Cdc25C antibody, anti-M phase inducer phosphatase 3 antibody, anti-Mitosis inducer CDC25 antibody, anti-MPIP3 antibody, anti-Phosphotyrosine phosphatase antibody |
| ProteinTarget: | Cdc25C2 |
| PackageSize: | 0.05 mg |
| GeneralRef: | General / background references:Bulavin DV et al. Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nat Cell Biol 5:545-51 (2003). |
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