| Catalog Code: | NB120-14231 |
| Product Type: | Primary Antibody |
| Product Name: | ATM Antibody |
| List Price: | 330 |
| Clonality: | Polyclonal |
| Gene ID: | 472 |
| Host: | Chicken |
| Isotype: | IgY |
| Product Description: | Chicken Polyclonal anti-ATM |
| Cross Reactivity: | Cross-reacts with Human and Mouse.Expected to cross-react with Pig (90% identity with immunogen) due to sequence homology.Not yet tested in other species. |
| Alternate Names: | anti-AT complementation group A antibody, anti-AT complementation group C antibody, anti-AT complementation group D antibody, anti-AT complementation group E antibody, anti-AT mutated protein antibody, anti-AT1 antibody, anti-ATA antibody, anti-Ataxia tel |
| Immunogen: | Synthetic peptide: YRSCYKVLIP HLVIRSHFDE VKSIANQIQE DWKSLLTDCF PKILVNILPY FAYEGTRDSG MAQQRETATK VYDMLKSENL LGKQI, corresponding to amino acids 1248-1332 of Human ATM. |
| Localization: | Primarily nuclear. Found also in endocytic vesicles in association with beta Adaptin. |
| Purity: | Immunogen affinity purified |
| Buffer: | Preservative: NoneConstituents: PBS |
| Packaging: | 50 micrograms |
| Package Size: | 0.05 mg |
| Concentration: | 1 mg/ml |
| Uses: | ICC: Use at a dilution of 1/200. IHC: Use at a dilution of 1/200. WB: Use at a dilution of 1/500. Predicted molecular weight: 370 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Application Summary: | ICC, IHC, WB |
| General References: | General / background references:Bakkenist CJ & Kastan MB DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421:499-506 (2003). |