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| Catalog Code: | NB120-14040 |
| Product Name: | IL8 Antibody |
| Product Description: | Chicken Polyclonal anti-IL8, conjugated to Biotin |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | Recombinant full length protein, corresponding to amino acids 28-99 of Human IL8. |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.05 mg Immunogen affinity purified Chicken IgY. |
| Uses: | ELISA: Use at an assay dependent dilution. WB: Use at a dilution of 1/500. Detects a band of approximately 8.9 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Secreted |
| Background: | IL8 is a member of the CXC chemokine family. This family of small basic heparan-binding proteins are proinflammatory and primarily mediate the activation and migration of neutrophils into tissue from peripheral blood. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types in response to an inflammatory stimulus. It functions as a chemoattractant, and is also a potent angiogenic factor. IL8 attracts neutrophils, basophils, and T-cells, but not monocytes. Cystic fibrosis (CF) is characterized by severe lung inflammation. The inflammatory process is believed to be caused by massive overproduction of the proinflammatory protein IL8, and the high levels of IL8 in the CF lung are therefore believed to be the central mechanism behind CF lung pathophysiology. |
| Storage: | 4 degree C for short term (weeks) and -20 degree C for long term. Avoid frequent freeze and thaw. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgY |
| Host Name: | Chicken |
| Buffer: | PBS |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu, |
| Alternate Names: | anti-310C antibody, AMCF 1 antibody, AMCF1 antibody, Beta thromboglobulin like protein antibody, CXC chemokine ligand 8 antibody, CXCL 8 antibody, CXCL8 antibody, Emoctakin antibody, GCP 1 antibody, GCP1 antibody, Granulocyte chemotactic protein 1 antibody, IL 8 antibody, Inteleukin 8 antibody, K 60 antibody, K60 antibody, LECT antibody, LUCT antibody, Lymphocyte derived neutrophil activating factor antibody, LYNAP antibody, MDNCF antibody, MONAP antibody, Monocyte derived neutrophil activating protein antibody, Monocyte derived neutrophil chemotactic factor antibody, NAF antibody, NAP 1 antibody, NAP1 antibody, Neutrophil activating factor antibody, Neutrophil activating peptide 1 antibody, Neutrophil activating protein 1 antibody, Protein 3 10C antibody, SCYB 8 antibody, SCYB8 antibody, T cell chemotactic factor antibody, TSG 1 antibody, TSG1 antibo |
| Package Size: | 0.05 mg |
| Preservative: | none |
| Conjugate: | Biotin |
| General References: | General / background references:Baldwin ET et al. Crystallization of human interleukin-8. A protein chemotactic for neutrophils and T-lymphocytes. J Biol Chem 265:6851-3 (1990). |
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