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| Catalog Code: | NB120-13522 |
| Product Name: | GOSR1 Antibody |
| Product Description: | Mouse Monoclonal anti-GOSR1 (HFD9-5) |
| Clone: | HFD9-5 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Concentration: | 1 mg/ml |
| Immunogen: | Rat liver Golgi-enriched membranes. |
| Cross Reactivity: | Cross-reacts with Mouse, Rat, Cow, Chicken, Dog, Hamster, Pig, Rabbit and Sheep. Not yet tested in other species. |
| Packaging: | 0.05 mg protein G purified Mouse IgG. |
| Uses: | ICC: Use at a concentration of 2 ug/ml. IM: Use at an assay dependent dilution. IP: Use at a concentration of 1 ug/ml. Western Blot: Use at a concentration of 2 ug/ml. Detects a band of approximately 28 kDa. Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Type IV membrane protein. Enriched on vesicular components at the terminal rims of the Golgi |
| Background: | This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | 50% Glycerol, PBS, 0.1mM PMSF. pH 7.2 |
| Application Summary: | Immunocytochemistry, immunofluorescence, immunoprecipitation, Western Blot, |
| Species Summary: | Bv, Ca, Ch, Ha, Hu, Mu, Po, Rt, Rb, Sh, |
| Alternate Names: | anti-28 kDa Golgi SNARE protein antibody, anti-Golgi SNAP receptor complex member 1 antibody, anti-Golgi SNARE 28 kDa antibody, anti-GOS28 antibody, anti-GOS28/P28 antibody, anti-GOSR1 antibody, anti-GS25 antibody, anti-P28 antibody |
| Package Size: | 0.05 mg |
| Preservative: | None |
| Notes Main: | For maximum product recovery centrifuge the product vial before removing cap. |
| General References: | This product has been used in:Espenshade PJ et al. Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER. Proc Natl Acad Sci U S A 99:11694-9 (2002). Hay JC et al. Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. Cell 89:149-58 (1997). Subramaniam VN et al. GS28, a 28-kilodalton Golgi SNARE that participates in ER-Golgi transport. Science 272:1161-3 (1996). Subramaniam VN et al. Monoclonal antibody HFD9 identifies a novel 28 kDa integral membrane protein on the cis-Golgi. J Cell Sci 108 ( Pt 6):2405-14 (1995). |
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