| CatalogCode: | NB120-11950 |
| ProductName: | E2F1 Antibody |
| Product Description: | Mouse Monoclonal anti-E2F1 (KH129) |
| Clone: | KH129 |
| Clonality: | Monoclonal |
| Immunogen: | Full-length protein corresponding to human E2F1. |
| CrossReactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.05 ml Mouse Tissue culture supernatant. |
| Uses: | WB: Use at a dilution of 1/500 - 1/1000. A band of approximately 60 kDa corresponding to E2F1 should be detected in Western blot analysis. An uncharacterized band of lower molecular weight may also be revealed under similar conditions. For optimal results, primary antibody incubations should be performed at 4 degrees C.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Nuclear |
| Control: | K-562 nuclear extract. |
| Background: | E2F's are DNA binding proteins, which associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. E2F1 is proposed to be involved in several cellular processes that range from tumor suppressor, cell progression and oncogenesis. E2F1 overexpression can also drive cells into apoptosis. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Tissue culture supernatant |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | PBS |
| ListPrice: | 285 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-E2F 1 antibody, anti-E2F transcription factor 1 antibody, anti-PBR 3 antibody, anti-PBR3 antibody, anti-PRB binding protein E2F 1 antibody, anti-PRB-binding protein E2F-1 antibody, anti-RBAP 1 antibody, anti-RBBP 3 antibody, anti-RBBP3 antibody, anti-RBP 3 antibody, anti-RBP3 antibody, anti-Retinoblastoma associated protein 1 antibody, anti-Retinoblastoma binding protein 3 antibody, anti-Transcription factor E2F1 antibody |
| ProteinTarget: | E2F1 |
| PackageSize: | 0.05 ml |