| CatalogCode: | NB120-11836 |
| ProductName: | DP2 Antibody |
| Product Description: | Rabbit Polyclonal anti-DP2 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide: SVSNLDLTTGATLPQS-K, with a C-terminal added lysine, conjugated to KLH, corresponding to amino acids 370-385 of Human DP2. |
| CrossReactivity: | Cross-reacts with Human.Expected to cross-react with Mouse (87% identity with immunogen) due to sequence homology.Not yet tested in other species. |
| Packaging: | 0.1 ml |
| Uses: | IF: Use at a dilution of 1/50. This concentration is determined by staining of transfected cells expressing recombinant human DP2.IP: Use at a dilution of 1/500. This concentration is sufficient to precipitate DP2 protein in transfected cells expressing recombinant human DP2.WB: Use at a dilution of 1/3000. This concentration is determined using a whole extract of transfected cells expressing recombinant human DP2 or in vitro translated DP2 protein. Detects a band of approximately 50 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Nuclear |
| Purity: | IgG purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Preservative: 15mM Sodium AzideConstituents: 0.01M PBS. pH 7.4 |
| ListPrice: | 330 |
| AppSummary: | IF, IP, WB |
| SpeciesSummary: | Hu |
| ProteinTarget: | DP2 |
| PackageSize: | 0.1 ml |
| GeneralRef: | General / background references:Cartwright P et al. E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription. Oncogene 17:611-23 (1998). Rogers KT et al. DP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivo. Proc Natl Acad Sci U S A 93:7594-9 (1996). Moberg K et al. E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry. Mol Cell Biol 16:1436-49 (1996). Hateboer G et al. Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins. Genes Dev 10:2960-70 (1996). |
| NotesMain: | Storage in frost-free freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours. |
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