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| Catalog Code: | NB120-11506 |
| Product Name: | gamma Catenin Antibody |
| Product Description: | Mouse Monoclonal anti-gamma Catenin (15F11) |
| Clone: | 15F11 |
| Clonality: | Monoclonal |
| ListPrice: | 560 |
| Immunogen: | Recombinant full length protein (Chicken). |
| Cross Reactivity: | Cross-reacts with Human, Cow, Chicken and Dog.Not yet tested in other species. |
| Packaging: | 0.1 ml raw Mouse ascites. |
| Uses: | ICC: Use at an assay dependent dilution. IF: Use at a dilution of 1/500. IHC-Fr: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. Western Blot: Use at a dilution of 1/1000. Predicted molecular weight: 82-86 kDa. Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cytoplasmic |
| Background: | Gamma Catenin is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of gamma Catenin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. It is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. |
| Storage: | Store at 4 degrees Celsius |
| Purity: | Ascites |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | Raw Ascites |
| Application Summary: | Immunocytochemistry, immunofluorescence, Immunohistochemistry-Frozen, immunoprecipitation, Western Blot, |
| Species Summary: | Bv, Ca, Hu, Fe, |
| Alternate Names: | anti-catenin (cadherin-associated protein) gamma (80kD) antibody, anti-Catenin gamma antibody, anti-CTNNG antibody, anti-Desmoplakin 3 antibody, anti-Desmoplakin III antibody, anti-Desmoplakin3 antibody, anti-DesmoplakinIII antibody, anti-DP 3 antibody, anti-DP III antibody, anti-DP3 antibody, anti-DPIII antibody, anti-gamma catenin antibody, anti-Junction plakoglobin antibody, anti-JUP antibody, anti-PDGB antibody, anti-PKGB antibody, anti-PLAKOGLOBIN antibody |
| Package Size: | 0.1 ml |
| Preservative: | 15mM Sodium Azide |
| General References: | General / background references:Reynolds AB et al. Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes. Mol Cell Biol 14:8333-42 (1994). Johnson KR et al. P- and E-cadherin are in separate complexes in cells expressing both cadherins. Exp Cell Res 207:252-60 (1993). Edelman GM & Crossin KL Cell adhesion molecules: implications for a molecular histology. Annu Rev Biochem 60:155-90 (1991). Takeichi M Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251:1451-5 (1991). |
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