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| Catalog Code: | NB120-11451 |
| Product Name: | IP10 Antibody |
| Product Description: | Mouse Monoclonal anti-IP10 (4D5) |
| Clone: | 4D5 |
| Clonality: | Monoclonal |
| ListPrice: | 315 |
| Concentration: | 1 mg/ml |
| Immunogen: | Recombinant human IP10. |
| Specificity: | ab11451 recognises both natural and recombinant human IP10. |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.25 mg Affinity purified Mouse IgG. |
| Uses: | ELISA: Use at a concentration of 1 - 2 ug/ml. WB: Use at an assay dependent dilution. Predicted molecular weight: 11.8 kDa. Is unsuitable for IHC-P or IHC-Fr.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end |
| Localization: | Secreted |
| Background: | Interferon-gamma-inducible 10 kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Affinity purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | PBS pH7.4 |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu, |
| Alternate Names: | anti-10 kDa interferon gamma induced protein antibody, anti-C7 antibody, anti-Chemokine (C X C motif) ligand 10 antibody, anti-Chemokine CXC motif ligand 10 antibody, anti-Crg 2 antibody, anti-CRG2 antibody, anti-CXCL 10 antibody, anti-CXCL10 antibody, anti-Gamma IP10 antibody, anti-gIP 10 antibody, anti-GIP10 antibody, anti-IFI 10 antibody, anti-IFI10 antibody, anti-INP 10 antibody, anti-INP10 antibody, anti-Interferon activated gene 10 antibody, anti-Interferon gamma induced cell line antibody, anti-Interferon inducible cytokine IP 10 antibody, anti-Interferon inducible cytokine IP10 antibody, anti-IP 10 antibody, anti-Mob 1 antibody, anti-MOB1 antibody, anti-SCYB 10 antibody, anti-SCYB10 antibody, anti-Small inducible cytokine B10 antibody, anti-Small inducible cytokine B10 precursor antibody, anti-Small inducible cytokine subfamily B (Cys X Cys) member 10 antibody, anti-Small inducible cytokine subfamily B CXC member 10 antibody |
| Package Size: | 0.25 mg |
| Preservative: | 0.09% Sodium azide |
| Notes Main: | Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use. |
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