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| Catalog Code: | NB120-11422 |
| Product Name: | ERp72 Antibody |
| Product Description: | Rabbit Polyclonal anti-ERp72 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | Synthetic peptide: KFIEEHATKLSRTKEEL, corresponding to amino acids 629-645 of Human ERp72. |
| Specificity: | This antibody detects ERp72 protein in human samples. |
| Cross Reactivity: | Cross-reacts with Human.Expected to cross-react with Mouse (88% identity with immunogen), Rat (88% identity with immunogen) and Pig (94% identity with immunogen) due to sequence homology.Not yet tested in other species. |
| Packaging: | 0.05 mg Immunogen affinity purified Rabbit IgG |
| Uses: | WB: Use at a concentration of 10 ug/ml. Detects a band of approximately 72 kDa, representing ERp72 in human fibrosarcoma HT 1080 cell lysate.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Endoplasmic reticulum |
| Background: | ERp72 is an endoplasmic reticulum luminal protein that is both a stress protein and a member of the protein disulfide isomerase family of proteins. Sequence analysis of ERp72 shows that it shares sequence identity with PDI (protein disulphide isomerase) at three discrete regions, as well as containing the ER retention signal KEEL at its C-terminus. ERp72 is shown to have three copies of sequence believed to be CGHC-containing active sites, which are also found in PDI. These CGHC sites are critical sites that are involved in the protein disulphide isomerization process. These results suggest that ERp72 is a newly described member of the family of CGHC-containing proteins that functions as a molecular chaperone. |
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | PBS |
| Application Summary: | Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-Calcium binding protein intestinal related antibody, anti-ERP 70 antibody, anti-ERP70 antibody, anti-ERP72 antibody, anti-PDIA 4 antibody, anti-PDIA4 antibody, anti-PDIR antibody, anti-Protein disulfide isomerase A4 antibody, anti-Protein disulfide isomerase associated 4 antibody, anti-Protein disulfide isomerase family A member 4 antibody, anti-Protein disulfide isomerase related protein antibody, anti-Protein ERp 72 antibody, anti-Protein ERp72 antibody |
| Package Size: | 0.05 mg |
| Preservative: | 1 mg/ml BSA and 0.01% sodium azide. |
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