| request information: |
|
| Catalog Code: | NB120-11322 |
| Product Name: | epsilon Tubulin Antibody |
| Product Description: | Mouse Monoclonal anti-epsilon Tubulin (TUB-11) |
| Clone: | TUB-11 |
| Clonality: | Monoclonal |
| ListPrice: | 360 |
| Concentration: | 2.4 mg/ml |
| Immunogen: | Synthetic peptide conjugated to KLH, corresponding to amino acids 352-366 of Human epsilon Tubulin. |
| Cross Reactivity: | Cross-reacts with Human, Mouse, Frog and Chicken.Not yet tested in other species. |
| Packaging: | 0.1 ml purified Mouse IgG. |
| Uses: | ELISA: Use at an assay dependent dilution. WB: Use at a concentration of 2 - 4 ug/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 52.9 kDa). Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Centrosomal; associated with pericentriolast material. |
| Background: | Microtubules constitute one of the major components of eukaryotic cells cytoskeleton and are involved in many essential processes, including cell division, ciliary and flagellar motility and intracellular transport. Microtubules of the eukaryotic cytoskeleton are composed of a heterodimer of a- and ß-tubulin. In addition to a- and ß-tubulin, several other tubulins have been identified, bringing the number of distinct tubulin classes to seven. Most of these tubulins have distinct subcellular localization and an emerging, diverse set of functions. Out of the seven different tubulins, four new members of the tubulin family have been identified including epsilon tubulin. Epsilon tubulin was found to be located in the centriolar area, a localization that is dependent on cell cycle modulation. |
| Storage: | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG2a |
| Host Name: | Mouse |
| Buffer: | Preservative: 15mM Sodium Azide Constituents: 1% BSA, 0.01M PBS. pH 7.4 |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu, Mu, Am, Ch |
| Alternate Names: | anti-dJ142L7.2 antibody, anti-FLJ22589 antibody, anti-OTTHUMP00000040425 antibody, anti-TUBE 1 antibody, anti-TUBE antibody, anti-TUBE1 antibody, anti-Tubulin epsilon 1 antibody, anti-Tubulin epsilon antibody, anti-Tubulin epsilon chain antibody |
| Package Size: | 0.1 ml |
| Notes Main: | Storage in frost-free freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours. |
| General References: | General / background references:Dutcher SK The tubulin fraternity: alpha to eta. Curr Opin Cell Biol 13:49-54 (2001). McKean PG et al. The extended tubulin superfamily. J Cell Sci 114:2723-33 (2001). Chang P & Stearns T Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function. Nat Cell Biol 2:30-5 (2000). |
order or
more information: | company product webpage |