| CatalogCode: | NB120-11214 |
| ProductName: | Cytokeratin Antibody |
| Product Description: | Mouse Monoclonal anti-Cytokeratin (PCK-26), conjugated FITC |
| Clone: | PCK-26 |
| Clonality: | Monoclonal |
| Immunogen: | Cytokeratin preparation from human epidermis. |
| Specificity: | NB120-11214 recognizes the 58 kD (cytokeratin 5), the 56 kD (cytokeratin 6) and the 52 kD (cytokeratin 8) bands in immunoblotting. ab11214 is a broad spectrum antibody which reacts specifically with a wide variety of normal, reactive and neoplastic epithelial tissues. The antibody reacts with simple, cornifying and non cornifying squamous epithelia and pseudostratified epithelia. It does not react with non-epithelial normal human tissues. |
| CrossReactivity: | NB 120-11214 cross reacts with cytokeratins from many species (e.g., rabbit, guinea pig, goat, bovine, sheep, rat, mouse, hamster, dog, cat, chicken, viper, lizard and carp). |
| Packaging: | 0.1 ml IgG purified Mouse ascites. |
| Uses: | IF: Use at a dilution of 1/25. |
| Background: | NB120-11214 may be used for the localization of cytokeratins using various immunochemical assays including direct immunofluorescence using frozen or fixed tissue sections or cultured cells. It may also be used in flow cytometry of normal and neoplastic epithelial cells. Intermediate-sized filaments are abundant cytoplasmic structural proteins in most vertebrate cells. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Constituents: 1% BSA, 0.01M PBS |
| ListPrice: | 295 |
| AppSummary: | IF, WB |
| SpeciesSummary: | Hu, Mu, Rt, Rb, Gp, Gt |
| ProteinTarget: | pan Cytokeratin |
| PackageSize: | 0.1 ml |
| Conjugate: | FITC |
| GeneralRef: | Lane EB & Alexander CM Use of keratin antibodies in tumor diagnosis. <i>Semin Cancer Biol</i> <b>1</b>:165-79 (1990). <PUBMED:1715788>Moll R <i>et al.</i> The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. <i>Cell</i> <b>31</b>:11-24 (1982). <PUBMED:6186379> |
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