| CatalogCode: | NB120-11013 |
| ProductName: | Caldesmon Antibody |
| Product Description: | Mouse Monoclonal anti-Caldesmon (CALD 5) |
| Clone: | CALD 5 |
| Clonality: | Monoclonal |
| Immunogen: | Turkey gizzard caldesmon was used as the immunogen. |
| Epitope: | This antibody is directed against an epitope located on the calmodulin non-binding part of the molecule. |
| Specificity: | The antibody localizes the high molecular weight form of caldesmon from chicken fibroblasts when used in immunoblotting. |
| CrossReactivity: | Cross-reacts with Human, Chicken and Turkey.Not yet tested in other species. |
| Packaging: | 0.1 ml |
| Uses: | DID: Use at an assay dependent dilution. IF: Use at an assay dependent dilution. By indirect immunofluorescence, this antibody stains frozen tissue sections from chicken, turkey, and human.WB: Use at a dilution of 1/100. A working dilution of 1/100 was determined by an immunoblot assay using a chicken gizzard extract and immunoperoxidase labeling.Caldesmon occurs in both a high molecular weight (120-150 kDa) and a low molecular weight (71-80 kDa) form, depending on the tissue in which it is located.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cytoplasmic |
| Background: | Monoclonal anti-Caldesmon may be used for the study of the involvement of caldesmon in contraction, cell movement, shape change, exocytosis and endocytosis. Caldesmon is an actin interacting and calmodulin binding protein found in smooth muscle and other cell types. Caldesmon occurs in both a high molecular weight (120-150 kDa) and a low molecular weight (71-80 kDa) form, depending on the tissue in which it is located. Caldesmon plays a major role in the regulation of smooth muscle and non-muscle contractile events. |
| Purity: | Ascites |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Preservative: 0.1% Sodium Azide Constituents: Raw Ascites |
| ListPrice: | 285 |
| AppSummary: | RID, IF, WB |
| ALTnames: | anti-CAD antibody, anti-CALD 1 antibody, anti-CALD1 antibody, anti-Caldesmon 1 antibody, anti-Caldesmon 1 Isoform 1 antibody, anti-Caldesmon 1 Isoform 2 antibody, anti-Caldesmon 1 Isoform 3 antibody, anti-Caldesmon 1 Isoform 4 antibody, anti-Caldesmon 1 Isoform 5 antibody, anti-Caldesmon1 antibody, anti-CDM antibody, anti-H CAD antibody, anti-HCAD antibody, anti-L CAD antibody, anti-LCAD antibody, anti-MGC21352 antibody, anti-NAG22 antibody |
| ProteinTarget: | Caldesmon |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Durard-Arczyrska, W., et al. Histochemistry 100, 465, (1993) |
| NotesMain: | Storage in frost-free freezers is not not recommended. If slight turbidity occurs upon prolonged storage, clarify by centrifugation before use. |
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