| request information: |
|
| Catalog Code: | NB120-10817 |
| Product Name: | HP1 gamma Antibody |
| Product Description: | Rat Monoclonal anti-HP1 gamma (MAC385) |
| Clone: | MAC385 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Full length M32 GST fusion protein. |
| Specificity: | Recognises the M32 molecule in mouse and the HP1 HS gamma molecule in man. |
| Cross Reactivity: | Cross-reacts with Human and Mouse.Not yet tested in other species. |
| Packaging: | 1 ml Rat Tissue culture supernatant. |
| Uses: | ELISA: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Nuclear |
| Background: | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. |
| Storage: | Store at +4oC or at -20oC if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we r |
| Purity: | Tissue culture supernatant |
| Isotype: | IgM |
| Host Name: | Rat |
| Application Summary: | ELISA , Immunohistochemistry-Frozen |
| Species Summary: | Hu, Mu, |
| Alternate Names: | anti-CBX 3 antibody, anti-CBX3 antibody, anti-Chromobox homolog 3 antibody, anti-Chromobox protein homolog 3 antibody, anti-GAMMA antibody, anti-HECH antibody, anti-Heterochromatin like protein 1 antibody, anti-Heterochromatin protein 1 homolog gamma antibody, anti-Heterochromatin protein HP1 gamma antibody, anti-HP1 gamma homolog antibody, anti-HP1Hs gamma antibody, anti-Modifier 2 protein antibody |
| Package Size: | 1 ml |
| Preservative: | 0.09% Sodium Azide |
| General References: | General / background references:Horsley D et al. M32, a murine homologue of Drosophila heterochromatin protein 1 (HP1), localises to euchromatin within interphase nuclei and is largely excluded from constitutive heterochromatin. Cytogenet Cell Genet 73:308-11 (1996). |
order or
more information: | company product webpage |