| CatalogCode: | NB120-10461 |
| ProductName: | Fas Antibody |
| Product Description: | Mouse Monoclonal anti-Fas (DX2) |
| Clone: | DX2 |
| Clonality: | Monoclonal |
| Immunogen: | Mouse L cells transfected with a human Fas/CD95 cDNA. |
| Epitope: | Monoclonal Anti-Human Fas (CD95/Apo1) - FITC Conjugate, reacts specifically with the functional epitope of the human Fas (CD95/Apo1) antigen. |
| CrossReactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.5 ml |
| Uses: | FACS: Use 100ul for 10<sup>6</sup> cells.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Plasma membrane (isoform 1) and Secreted (isoforms 2-6). |
| Control: | Burkitt?s lymphoma Raji cells. |
| Purity: | Protein A purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Preservative: 15mM Sodium AzideConstituents: 1% BSA, 0.01M PBS. pH 7.4 |
| ListPrice: | 330 |
| AppSummary: | FACS |
| ALTnames: | anti-ALPS1A antibody, anti-APO-1 antibody, anti-APT1 antibody, anti-Apo-1 Fas antibody, anti-CD95 antibody, anti-FAS1 antibody, anti-FASTM antibody, anti-TNFRSF6 antibody |
| ProteinTarget: | Fas |
| PackageSize: | 0.05 ml |
| GeneralRef: | General / background references:Stohl W et al. CD95 (Fas)-based, superantigen-dependent, CD4+ T cell-mediated down-regulation of human in vitro immunoglobulin responses. J Immunol 160:5231-8 (1998). Caricchio R et al. Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocyte apoptosis. J Immunol 161:241-51 (1998). Choe J et al. Cellular and molecular factors that regulate the differentiation and apoptosis of germinal center B cells. Anti-Ig down-regulates Fas expression of CD40 ligand-stimulated germinal center B cells and inhibits Fas-mediated apoptosis. J Immunol 157:1006-16 (1996). |
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