| Catalog Code: | NB120-10460 |
| Product Type: | Primary Antibody |
| Product Name: | Fas Antibody |
| List Price: | 330 |
| Clonality: | Monoclonal |
| Gene ID: | 355 |
| Host: | Mouse |
| Clone: | DX2 |
| Isotype: | IgG1 |
| Product Description: | Mouse Monoclonal anti-Fas (DX2) |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Alternate Names: | anti-ALPS1A antibody, anti-APO-1 antibody, anti-APT1 antibody, anti-Apo-1 Fas antibody, anti-CD95 antibody, anti-FAS1 antibody, anti-FASTM antibody, anti-TNFRSF6 antibody |
| Immunogen: | Mouse L cells transfected with a human Fas/CD95 cDNA. |
| Epitope: | Monoclonal Anti-Human Fas (CD95/Apo1) reacts specifically with the functional epitope of human Fas (CD95/Apo1) antigen. By immunoblotting, it recognizes the denatured non-reduced 1-173 amino acid residues of a recombinant, human Fas preparation. |
| Localization: | Plasma membrane (isoform 1) and Secreted (isoforms 2-6). |
| Purity: | Protein A purified |
| Buffer: | Preservative: 15mM Sodium AzideConstituents: 0.01M PBS. pH 7.4 |
| Packaging: | 25 micrograms |
| Package Size: | 0.025 mg |
| Concentration: | 2 mg/ml |
| Uses: | FACS: Use 100ul for 10<sup>6</sup> cells.WB: Use at an assay dependent dilution. Predicted molecular weight: 45-48 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Application Summary: | FACS, WB |
| General References: | General / background references:Stohl W et al. CD95 (Fas)-based, superantigen-dependent, CD4+ T cell-mediated down-regulation of human in vitro immunoglobulin responses. J Immunol 160:5231-8 (1998). Caricchio R et al. Fas/Fas ligand intera |