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| Catalog Code: | NB120-10435 |
| Product Name: | Mitochondrial p110 Antibody |
| Product Description: | Mouse Monoclonal anti-Mitochondrial p110 (2G2) |
| Clone: | 2G2 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | Recombinant full length protein (Human). |
| Cross Reactivity: | Cross-reacts with Human and Monkey. Not yet tested in other species. |
| Packaging: | 0.025 mg |
| Uses: | IF: Use at an assay dependent dilution. WB: Use at a concentration of 2 - 10 ug/ml. Detects a band of approximately 110 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Mitochondrial |
| Background: | p110 has an approximate isoelectric point of 6.5 and co-partitions with HSP-60 proteins during isolation of mitochondria from HeLa cells. Close examination of the staining pattern in HeLa and Fanconi?s anemia cells reveal differences in the morphology and organization of mitochondria in these two cell types. In HeLa cells, mitochondria appear as individual tubular compartments of variable length and are closely associated with vimentin filaments, particularly at the periphery of the nucleus. In Fanconi?s anemia cells, mitochondria have a filamentous shape and form an interconnected cytoplasmic reticulum running in parallel with both vimentin filaments and microtubules. |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | Preservative: 0.08% Sodium Azide Constituents: PBS. pH 7.4 |
| Application Summary: | immunofluorescence, Western Blot |
| Species Summary: | Hu, Mk |
| Package Size: | 0.025 mg |
| General References: | This product has been used in:Paulin-Levasseur M et al. The 2G2 antibody recognizes an acidic 110-kDa human mitochondrial protein. Histochem J 30:617-25 (1998). |
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