| CatalogCode: | NB120-10089 |
| ProductName: | IL2 Antibody |
| Product Description: | Mouse Monoclonal anti-IL2 (14-0) |
| Clone: | 14-0 |
| Clonality: | Monoclonal |
| Immunogen: | Recombinant full length protein (Human). |
| CrossReactivity: | Expected to cross-react with Human.Not yet tested in other species. |
| Packaging: | 0.2 mg protein G purified Mouse IgG. |
| Uses: | ELISA: Use at an assay dependent dilution. Suitable for sandwich ELISA of IL2 in the following combination: capture: ab10090 / conjugate: ab10089.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Secreted |
| Background: | Human interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | protein G purified |
| Isotype: | IgG2a |
| Host_Name: | Mouse |
| Buffer: | PBS. pH 7.4 |
| ListPrice: | 285 |
| AppSummary: | ELISA |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Aldesleukin antibody, anti-Interleukin 2 antibody, anti-Lymphokine antibody, anti-T Cell Growth Factor antibody, anti-TCGF antibody |
| ProteinTarget: | IL2 |
| PackageSize: | 0.2 mg |
| NotesMain: | Concentration varies from lot to lot and can be provided on request. |
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