| CatalogCode: | NB120-10062 |
| ProductName: | GFAP Antibody |
| Product Description: | Mouse Monoclonal anti-GFAP (GF5) |
| Clone: | GF5 |
| Clonality: | Monoclonal |
| Immunogen: | This clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunised with purified glial fibrillary acidic protein from human brain. |
| Specificity: | There is no cross-reactivity with other neurospecific proteins. |
| CrossReactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 02 mg protein G purified Mouse IgG. |
| Uses: | ELISA: Use at an assay dependent dilution. IF: Use at an assay dependent dilution. IHC: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 43-45 kDa corresponding to GFAP in human brain and spinal cord extract. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cytoplasmic |
| Background: | Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | protein G purified |
| Isotype: | IgG2b |
| Host_Name: | Mouse |
| Buffer: | PBS. pH 7.4 |
| ListPrice: | 285 |
| AppSummary: | ELISA, IF, IHC, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Astrocyte antibody, anti-FLJ45472 antibody, anti-GFAP antibody, anti-Glial Fibrillary Acidic Protein antibody |
| ProteinTarget: | GFAP Astrocyte Marker |
| PackageSize: | 02 mg |
| NotesMain: | Concentration varies from lot to lot and can be provided on request. |
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