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| Catalog Code: | NB120-10032 |
| Product Name: | MUC16 Antibody |
| Product Description: | Mouse Monoclonal anti-MUC16 (X306) |
| Clone: | X306 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 5.6 mg/ml |
| Immunogen: | Full length native protein (purified from human ovarian carcinoma). |
| Specificity: | Epitope specificity group A (ISOBM classification). |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.5 mg IgG purified Mouse ascites. |
| Uses: | WB: Detects a band of >1000 kDa. Can be used in ELISA. Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cell membrane; Single pass type I membrane protein. Secreted, extracellular space. |
| Background: | CA125/MUC16 antigen is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that CA125/MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa. |
| Storage: | Store at 4 degrees C long term. |
| Purity: | IgG purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | 0.15M Sodium Chloride, 10mM Tris. pH 7.5 |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu, |
| Alternate Names: | anti-CA 125 antibody, anti-CA125 antibody, anti-CA125 ovarian cancer antigen antibody, anti-FLJ14303 antibody, anti-MUC 16 antibody, anti-Mucin 16 antibody, anti-Mucin 16 cell surface associated antibody, anti-Mucin16 antibody, anti-Ovarian cancer related tumor marker CA125 antibody, anti-Ovarian carcinoma antigen CA125 antibody |
| Package Size: | 0.5 mg |
| Preservative: | Sodium Azide |
| Notes Main: | This antibody can be used in a sandwich ELISA (coating - conjugate) with the following clone: X75 - X306 For Sandwich ELISA pair this antibody with: NB600-1468 |
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