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| Catalog Code: | NB110-8394 |
| Product Name: | IL2 Antibody |
| Product Description: | Mouse Monoclonal anti-IL2 (43-2) |
| Clone: | 43-2 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Recombinant full length protein (Human). |
| Cross Reactivity: | Expected to cross-react with Human.Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | ELISA: Suitable for sandwich ELISA of IL2 in the following combination: capture: NB120-10090 / conjugate: NB120-10089. Optimal dilutions and concentrations should be determined by the end user. |
| Localization: | Secreted |
| Background: | Human interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells. |
| Storage: | + 4 °C |
| Purity: | protein G purified |
| Isotype: | IgG2a |
| Host Name: | Mouse |
| Buffer: | PBS. pH 7.4 |
| Application Summary: | ELISA assay dependent |
| Species Summary: | Hu |
| Alternate Names: | anti-Aldesleukin antibody, anti-Interleukin 2 antibody, anti-Lymphokine antibody, anti-T Cell Growth Factor antibody, anti-TCGF antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.1% Sodium Azide |
| Notes Main: | This antibody can be used in a sandwich ELISA (coating - conjugate) with the following clone: 43-2 - 14-0 For Sandwich ELISA pair this antibody with: NB120-10089 |
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