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| Catalog Code: | NB110-8389 |
| Product Name: | IL3 Antibody |
| Product Description: | Mouse Monoclonal anti-IL3 (2F2) |
| Clone: | 2F2 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Recombinant full length protein (Human). |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | ELISA Suitable for sandwich ELISA of IL3 in the following combination: capture - NB120-10084, NB120-10080, NB120-10083, conjugate NB120-10082. Optimal dilutions and concentrations should be determined by the end user. |
| Localization: | Secreted |
| Background: | The pleiotropic IL3 (Interleukin 3) is a 15kDa cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL3 acts in hematopoiesis by controlling the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and the monocytes/macrophages. It induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes and is expressed by activated T cells, mast cells, and natural killer cells. IL3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL3 has also been shown to protect mast cells from undergoing apoptosis. |
| Storage: | + 4 °C |
| Purity: | protein G purified |
| Isotype: | IgG2a |
| Host Name: | Mouse |
| Buffer: | PBS. pH 7.4 |
| Application Summary: | ELISA assay dependent |
| Species Summary: | Hu |
| Alternate Names: | anti-Burst promoting activity antibody, anti-Colony stimulating factor multiple antibody, anti-Eosinophil colony stimulating factor antibody, anti-Hematopoietic growth factor antibody, anti-IL 3 antibody, anti-Interleukin 3 antibody, anti-Mast cell growth factor antibody, anti-MCGF antibody, anti-MGC79398 antibody, anti-MGC79399 antibody, anti-Multi CSF antibody, anti-Multilineage colony stimulating factor antibody, anti-Multipotential colony stimulating factor antibody, anti-P cell stimulating factor antibody, anti-Thy1 inducing factor antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.1% Sodium Azide |
| Notes Main: | This antibody can be used in a sandwich ELISA (coating - conjugate) with the following clone: 2F2 - 3C11 For Sandwich ELISA pair this antibody with: NB120-10082 |
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