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| Catalog Code: | NB110-8385 |
| Product Name: | Ferritin Antibody |
| Product Description: | Mouse Monoclonal anti-Ferritin (F31) |
| Clone: | F31 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 2.4 mg/ml |
| Immunogen: | This clone has been derived from hybridization of SP2/0 myeloma cells with spleen cells of Balb/c mice immunised with purified human ferritin. |
| Packaging: | 0.2 mg protein G purified Mouse ascites. |
| Uses: | ELISA: Use at an assay dependent dilution. Can be used with clone F23 (capture). |
| Background: | Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and soluble form. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits of two types, H (heavy; 21 kDa) and L (light; 19 kDa), and is capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiological status of the cell, the ratio of H to L subunits in ferritin can vary widely. Ferritin is found in the liver, spleen, kidney and heart, with smaller amounts being found in blood. Serum ferritin levels serve as an indicator of the amount of iron stored in the body. Serum ferritin is the most sensitive test for anaemia, and is also used as a marker for restless leg syndrome, hemochromatosis and porphyria. As ferritin is an acute-phase reactant, it is often elevated during infection. Defects in ferritin proteins are associated with several neurodegenerative diseases. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | protein G purified |
| Isotype: | IgG2b |
| Host Name: | Mouse |
| Buffer: | PBS. pH 7.4 |
| Application Summary: | ELISA Use at an assay dependent dilution |
| Species Summary: | Hu |
| Alternate Names: | anti-Ferritin L subunit antibody, anti-Ferritin light chain antibody, anti-Ferritin light polypeptide like 3 antibody, anti-FTL antibody, anti-FTMT antibody, anti-Mitochondrial ferritin antibody, anti-MTF antibody |
| Package Size: | 0.2 mg |
| Preservative: | 0.1% Sodium Azide |
| Notes Main: | This antibody can be used in a sandwich ELISA (coating - conjugate) with the following clone: F23 - F31 For Sandwich ELISA pair this antibody with: NB110-8384 |
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