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| Catalog Code: | NB110-8085 |
| Product Name: | Thyroglobulin Antibody |
| Product Description: | Mouse Monoclonal anti-Thyroglobulin (5F9) |
| Clone: | 5F9 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Thyroglobulin from human thyroid gland. |
| Specificity: | This antibody does not interfere with anti-thyroglobulin autoantibodies. |
| Cross Reactivity: | Cross-reacts with Human and Cow.Not yet tested in other species. |
| Packaging: | 1 mg protein G purified Mouse ascites. |
| Uses: | ELISA: Can be used in an ELISA pair with NB120-1982 (conjugate). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Secreted |
| Background: | The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto?s thyroiditis, Graves? diseases), with the highest level observed in Hashimoto?s thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients. |
| Storage: | + 4 °C |
| Purity: | protein G purified |
| Isotype: | IgG2a |
| Host Name: | Mouse |
| Buffer: | PBS |
| Application Summary: | ELISA assay dependent |
| Species Summary: | Hu, Bv |
| Alternate Names: | anti-AITD 3 antibody, anti-AITD3 antibody, anti-hTG antibody, anti-Tgn antibody |
| Package Size: | 1 mg |
| Preservative: | 0.1% Sodium Azide |
| Notes Main: | This antibody can be used in a sandwich ELISA (coating - conjugate) with the following clone: 5F9 - 5E6 For Sandwich ELISA pair this antibody with: NB110-8083 |
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