| CatalogCode: | | NB110-8083 |
| ProductName: | | Thyroglobulin Antibody |
| Product Description: | | Mouse Monoclonal anti-Thyroglobulin (5E6) |
| Clone: | | 5E6 |
| Clonality: | | Monoclonal |
| Immunogen: | | Thyroglobulin from human thyroid gland. |
| Specificity: | | This antibody does not interfere with anti-thyroglobulin autoantibodies. |
| CrossReactivity: | | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | | 1 mg |
| Uses: | | ELISA: Use at an assay dependent dilution. Can be used in an ELISA pair with ab1984 as coating.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | | Secreted |
| Background: | | The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3.Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto?s thyroiditis, Graves? diseases), with the highest level observed in Hashimoto?s thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients. |
| Isotype: | | IgG2b |
| Host_Name: | | Mouse |
| Buffer: | | PBS. pH 7.4 |
| ListPrice: | | 295 |
| AppSummary: | | ELISA |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-AITD3 antibody, anti-hTG antibody, anti-Tgn antibody |
| ProteinTarget: | | Thyroglobulin [5E6] |
| PackageSize: | | 1 mg |
| NotesMain: | | Concentration varies from lot to lot and can be provided on request. |
| more information: | | company product webpage |