| CatalogCode: | NB110-8021 |
| ProductName: | Insulin Antibody |
| Product Description: | Mouse Monoclonal anti-Insulin (7F5) |
| Clone: | 7F5 |
| Clonality: | Monoclonal |
| Immunogen: | Full length native protein (purified). |
| Specificity: | Kass for this antibody is 1.0 x 109M-1. It cross-reacts with human proinsulin. No cross-reaction with free C-peptide. |
| CrossReactivity: | Cross-reacts with Human and Pig. Expected to cross-react with Cow (30%). Not yet tested in other species. |
| Packaging: | 0.1 mg protein A purified Mouse ascites. |
| Uses: | ELISA: Use at an assay dependent dilution. Not tested in other applications. |
| Localization: | Secreted |
| Background: | Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | protein A purified |
| Isotype: | IgG1 kappa |
| Host_Name: | Mouse |
| Buffer: | PBS. pH 7.4 |
| ListPrice: | 295 |
| AppSummary: | ELISA |
| SpeciesSummary: | Hu, Po |
| ALTnames: | anti-Insulin precursor antibody |
| ProteinTarget: | Insulin |
| PackageSize: | 0.1 mg |
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