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| Catalog Code: | NB110-7904 |
| Product Name: | Transferrin Antibody |
| Product Description: | Mouse Monoclonal anti-Transferrin (8B9) |
| Clone: | 8B9 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Placental transferrin receptor or transferrin. |
| Specificity: | Human transferrin. |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.1 mg protein A purified Mouse ascites. |
| Uses: | ELISA: Use at an assay dependent dilution. Will detect transferrin in serum by sandwich ELISA as an antibody pair. Use NB120-10212 as the coating agent with either NB120-10208 or NB120-10209 for detection. Will detect transferrin-transferrin receptor complex when used as an antibody pair with an anti-transferrin receptor antibody.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Secreted |
| Background: | Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum. |
| Storage: | + 4 °C |
| Purity: | protein A purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | PBS. pH 7.4 |
| Application Summary: | ELISA |
| Species Summary: | Hu |
| Alternate Names: | anti-Beta 1 metal binding globulin antibody, anti-PRO1400 antibody, anti-PRO1557 antibody, anti-PRO2086 antibody, anti-Serotransferrin precursor antibody, anti-Siderophilin antibody, anti-TF antibody, anti-Transferin antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.1% Sodium Azide |
| Notes Main: | This antibody can be used in a sandwich ELISA (coating - conjugate) with the following clone: 23D10 - 8B9 For Sandwich ELISA pair this antibody with: NB110-8468 |
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