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| Catalog Code: | NB110-74948 |
| Product Name: | TRP4 Antibody |
| Product Description: | Rabbit Polyclonal anti-TRP4 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Omim ID: | ALPHA TRPC4_RAT ; BETA TRPC4_RAT ; BETA-2 TRPC4_RAT |
| Immunogen: | A synthetic peptide as a part of rat (and isoforms: alpha, beta, beta-2 TRPC4 (TRP4) conjugated to immunogenic carrier protein was used as the immunogen. |
| Specificity: | Appears to be specific for TRPC4. See also the immunogen. |
| Cross Reactivity: | Rat. Other species not yet tested. |
| Packaging: | 0.1 ml of Whole antisera antibody |
| Uses: | IHC, WB. A dilution of 1 : 300 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user. |
| Background: | FUNCTION: Thought to form non-selective a receptor-activated calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion.; SUBUNIT: Isoform alpha but not isoform beta associates with inositol-1,4,5-triphosphate receptor (ITPR).; SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Probable). |
| Storage: | Store at 4C for short-term. Aliquot and store at -20C for long term. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Host Name: | Rabbit |
| Buffer: | Lyophilised in PBS |
| Application Summary: | immunohistochemistry , Western Blot 1:300 to 1:3000 |
| Species Summary: | Rt |
| Alternate Names: | anti-Transient receptor potential channel 4 alpha splice variant antibody, anti-Trpc4_v2 antibody, anti-Trpc4 antibody, anti-Transient receptor potential channel 4 beta splice variant antibody, anti-Transient receptor potential channel 4 beta-2 splice variant antibody, anti-Trpc4 antibody |
| Package Size: | 0.1 ml |
| Preservative: | No Preservative |
| Notes Main: | Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material. Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| General References: | 1. Schaefer M, et al. J. Biol. Chem. 277:3752-3759(2002). 2. Funayama M, et al. Brain Res. Mol. Brain Res. 43:259-266(1996). 3. Tang Y, et al. J. Biol. Chem. 275:37559-37564(2000). |
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more information: | company product webpage |