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| Catalog Code: | NB110-74800 |
| Product Name: | ULK1 Antibody |
| Product Description: | Sheep Polyclonal anti-ULK1 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Omim ID: | ULK1_HUMAN ; ULK1_RAT ; ULK1_MOUSE |
| Immunogen: | A synthetic peptide as a part of human, rat, mouse serine/threonine-protein kinase ULK1 (ULK1, ATG1, UNC51, Unc51.1, KIAA0722) conjugated to immunogenic carrier protein has been used as the immunogen. |
| Specificity: | Appears to be specific for ULK1. |
| Cross Reactivity: | Human, mouse and rat. Other species not yet tested. |
| Packaging: | 0.5 mg of IgG purified antibody |
| Uses: | IHC, WB. Use at a concentration of 1-10 µg/ml. The optimal workiing concentration should be determined by the end user. |
| Background: | FUNCTION: Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells.; CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.; SUBUNIT: Interacts with GABARAP and GABARAPL2. |
| Storage: | Store at 4C for short-term. Aliquot and store at -20C for long term. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG |
| Host Name: | Sheep |
| Buffer: | Lyophilised in PBS |
| Application Summary: | immunohistochemistry, Western Blot 1-10 µg/ml |
| Species Summary: | Hu, Mu, Rt |
| Alternate Names: | anti-Unc-51-like kinase 1 antibody, anti-serine/threonine-protein kinase Unc51.1 KIAA0722 antibody, anti-ULK1 antibody, anti-ATG1 antibody, anti-UNC51 antibody, anti-Unc51.1 antibody, anti-unc-51-like kinase 1 (C. elegans) antibody, anti-FLJ38455 antibody |
| Package Size: | 0.5 mg |
| Preservative: | No Preservative |
| Notes Main: | Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material. Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| General References: | 1. Chan E.Y, et al. J. Biol. Chem. 282 (35), 25464-25474(2007). 2. Wissing J, et al. Mol. Cell Proteomics 6 (3), 537-547(2007). 3. Olsen J.V, et al. Cell 127 (3), 635-648(2006). 4. Young A.R, et al. J. Cell. Sci. 119 (PT 18), 3888-3900(2006). 5. Tomoda T, et al. Genes Dev. 18 (5), 541-558(2004). 6. Okazaki N, et al. Brain Res. Mol. Brain Res. 85 (1-2), 1-12(2000). 7. Kuroyanagi H, et al. Genomics 51 (1), 76-85(1998). |
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