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| Catalog Code: | NB110-74753 |
| Product Name: | OMP Antibody |
| Product Description: | Rabbit Polyclonal anti-OMP |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Omim ID: | OMP_RAT ; OMP_MOUSE |
| Immunogen: | A synthetic peptide as a part of rat Olfactory Marker Protein (OMP) conjugated to immunogenic carrier protein has been used as the immunogen. The peptide is homologous with the corresponding sequence derived from OMP protein in mouse. |
| Specificity: | Highly specific for mature olfactory neurons (including axon and terminals). |
| Cross Reactivity: | Rat, mouse, hamster and human. Other species have not yet been tested. |
| Packaging: | 0.5 mg of IgG purified antibody |
| Uses: | IHC, WB. Use at a concentration of 1-5 µg/ml. The optimal dilution should be determined by the end user. For IHC, Zamboni's or 4% PFA fixatives are recommended. |
| Localization: | Cytoplasmic |
| Background: | Olfactory marker protein (OMP) is an abundant, 19-kDa, cytosolic protein that is almost exclusively expressed in mature, functioning, olfactory neurons but not in the neural precursor basal cells. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Its tissue-specific expression in the receptor cells together with the results of the mouse knockout studies show that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. FUNCTION: May act as a modulator of the olfactory signal-transduction cascade. SUBUNIT: Interacts with BEX1 and BEX2. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Uniquely associated with mature olfactory receptor neurons. SIMILARITY: Belongs to the olfactory marker protein family. ; ; |
| Storage: | Store at 4C for short-term. Aliquot and store at -20C for long term. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | Lyophilised in PBS |
| Application Summary: | immunohistochemistry, Western Blot 1-5 µg/ml. |
| Species Summary: | Rt, Mu, Ha, Hu |
| Alternate Names: | Anti-Olfactory marker protein antibody |
| Package Size: | 0.5 mg |
| Preservative: | No Preservative |
| Notes Main: | Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material. Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| General References: | 1. Margolis, F. L. Scand J Immunol Suppl. 9: 181-99 (1982) 2. Moriya-Ito et al. Chem. Senses 30 (2), 111-119 (2005) 3. Baldisseri et al. J. Mol. Biol. 319 (3), 823-837 (2002) 4. Rogers et al. Proc. Natl. Acad. Sci. U.S.A. 84 (6), 1704-1708 (1987) 5. Grillo, M. et al. Int J Dev Neurosci. 14 (7-8), 813-22 (1996) 6. Margolis, J. W. et al. J Biomol NMR. 33 (1), 63-8 (2005) |
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