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| Catalog Code: | NB110-74729 |
| Product Name: | OPSG OPSR Antibody |
| Product Description: | Rabbit Polyclonal anti-OPSG OPSR |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Omim ID: | OPSG_HUMAN ; OPSR_HUMAN |
| Immunogen: | A synthetic peptide as a part of human OPSG and OPSR (green & red-sensitive opsin, OPN1MW, OPN1LW, GCP, RCP, CBBM, opsin 1) conjugated to immunogenic carrier protein was used as the immunogen. |
| Specificity: | Appears to be specific for OPSG and OPSR. |
| Cross Reactivity: | Human. Other species not yet tested. |
| Packaging: | 0.1 ml of Whole antisera antibody |
| Uses: | IHC, WB. A dilution of 1 : 300 to 1 : 4000 is recommended. The optimal dilution should be determined by the end user. |
| Background: | FUNCTION: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.; BIOPHYSICOCHEMICAL PROPERTIES:; Absorption: Abs(max)=530 nm;; SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.; TISSUE SPECIFICITY: The three color pigments are found in the cone photoreceptor cells.; PTM: Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.; DISEASE: Defects in OPN1MW are the cause of partial colorblindness deutan series (CBD); also called deuteranopia. |
| Storage: | Store at 4C for short-term. Aliquot and store at -20C for long term. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Host Name: | Rabbit |
| Buffer: | Lyophilised in PBS |
| Application Summary: | immunohistochemistry, Western Blot 1:300 |
| Species Summary: | Hu |
| Alternate Names: | anti-Green-sensitive opsin antibody, anti-green cone photoreceptor pigment antibody, anti-OPN1MW antibody, anti-OPN1LW antibody, anti-GCP antibody, anti-RCP antibody, anti-CBBM antibody, anti-OPN1MW1 antibody, anti-opsin 1 (cone pigments) antibody, anti-medium-wave-sensitive (color blindness antibody, anti-deutan) antibody, anti-red-sensitive opsin antibody, anti-red cone photoreceptor pigment antibody, anti-M opsin antibody |
| Package Size: | 0.1 ml |
| Preservative: | No Preservative |
| Notes Main: | Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material. Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| General References: | 1. Nathans J, et al. Science 232:193-202(1986). 2. Applebury M.L, et al. Vision Res. 26:1881-1895(1986). 3. Winderickx J, et al. Nat. Genet. 1:251-256(1992). |
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