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| Catalog Code: | NB110-74723 |
| Product Name: | OPN5 Antibody |
| Product Description: | Rabbit Polyclonal anti-OPN5 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Omim ID: | OPN5_HUMAN |
| Immunogen: | A synthetic peptide as a part of human opsin-5 (OPN5, opsin 5, neuropsin, GPR136, PGR12, TMEM13) conjugated to immunogenic carrier protein was used as the immunogen. |
| Specificity: | Appears to be specific for opsin-5. |
| Cross Reactivity: | Human. Other species not yet tested. |
| Packaging: | 0.1 ml of Whole antisera antibody |
| Uses: | IHC, WB. A dilution of 1 : 300 to 1 : 4000 is recommended. The optimal dilution should be determined by the end user. |
| Localization: | Membrane; Multi-pass membrane protein. |
| Background: | Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this gene may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants encoding different isoforms. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Detected in brain and retina and cell lines derived from neural retina. |
| Storage: | Store at 4C for short-term. Aliquot and store at -20C for long term. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Host Name: | Rabbit |
| Buffer: | Lyophilised in PBS |
| Application Summary: | immunohistochemistry, Western Blot 1:300 |
| Species Summary: | Hu |
| Alternate Names: | anti-GPCR GPR136 antibody, anti-Gpr136 antibody, anti-G protein-coupled receptor 136 antibody, anti-G-protein coupled receptor PGR12 antibody, anti-HGNC:21318 antibody, anti-Neuropsin antibody, anti-OPN5 antibody, anti-Opsin 5 antibody, anti-PGR12 antibody, anti-TMEM13 antibody, anti-Transmembrane protein 13 antibody |
| Package Size: | 0.1 ml |
| Preservative: | No Preservative |
| Notes Main: | Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material. Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| General References: | 1. Tarttelin E.E, et al. FEBS Lett. 554:410-416(2003). 2. Fredriksson R, et al. FEBS Lett. 554:381-388(2003). 3. Vassilatis D.K, et al. Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003). 4. Mungall A.J, et al. Nature 425:805-811(2003). |
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more information: | company product webpage |