| Catalog Code: | NB110-66655 |
| Product Type: | Primary Antibody |
| Product Name: | ATM Antibody |
| List Price: | 295 |
| Clonality: | Monoclonal |
| Gene ID: | 472 |
| Host: | Rabbit |
| Clone: | EP1890Y |
| Isotype: | IgG |
| Product Description: | Rabbit Monoclonal anti-ATM (EP1890Y) [Ser1981] |
| Phosphorylated: | Ser1981 |
| Cross Reactivity: | This antibody is reactive against Human. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | ATM is a nuclear phosphoprotein involved in Ataxia-telangiectasia (A-T) an autosomal recessive disorder characterized by cerebellar ataxia, immune deficiencies, increased cancer predisposition, chromosomal instability and radiation sensitivity (1-2). This |
| Alternate Names: | Anti-AT complementation group A antibody, Anti-AT complementation group C antibody, Anti-AT complementation group D antibody, Anti-AT complementation group E antibody, Anti-AT mutated antibody, Anti-AT protein antibody, Anti-AT1 antibody, Anti-ATA antibod |
| Immunogen: | A synthetic peptide corresponding to residues surrounding serine 1981 of human ATM was used as an immunogen. |
| Specificity: | This antibody detects serine 1981 of human ATM. |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Preservative: | 0.01% sodium azide |
| Packaging: | 0.1 ml Rabbit ascites. |
| Package Size: | 0.1 ml |
| Uses: | This antibody is useful for Western Blot, Immunohistochemistry, ICC, and Immunoprecipitation. |
| Application Summary: | IHC, IP, WB, ICC |
| Storage: | Aliquot and store at -20 °C. |
| General References: | 1. Harnden, D.G.; Int. J. Radiat. Biol. 66:S13-S19, 1994. 2. Lavin MF, Shiloh,Y. Ann. Rev. Imm. 15:177-202, 1997 3. Goldstine JV, et al. DNA Repair, 5:432-443, 2006. 4. Savitsky K et al. Hum. Mol. Gen. 4:2025-2032, 1995. 5. Stankovic T.et al. Lancet 3 |
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