| Catalog Code: | NB110-66653 |
| Product Type: | Primary Antibody |
| Product Name: | TrkB Antibody |
| List Price: | 295 |
| Clonality: | Monoclonal |
| Gene ID: | 4915 |
| Host: | Rabbit |
| Clone: | EP1298Y |
| Isotype: | IgG |
| Product Description: | Rabbit Monoclonal anti-TrkB (EP1298Y) [Tyr817] |
| Phosphorylated: | Tyr817 |
| Cross Reactivity: | This antibody is reactive against Human and Rat. Not yet tested in other species. |
| Species Summary: | Hu, Rt |
| Background: | There is increasing evidence that neutrophins and their receptors play an important role in regulating development of both the central and the peripheral nervous systems (1). The binding of neurotrophin ligands to their respective Trk cellular receptors i |
| Alternate Names: | Anti-BDNF/NT 3 growth factors receptor antibody; Anti-brain derived neurotrophic factor receptor antibody; Anti-GP145 TrkB antibody; Anti-GP95 TrkB antibody; Anti-neurotrophic tyrosine kinase receptor type 2 antibody; Anti-Neurotrophin receptor tyrosine k |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Tyrosine 817 of human TrkB was used as an immunogen. |
| Specificity: | This antibody detects TrkB phosphorylated at Y817. |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Preservative: | 0.01% sodium azide |
| Packaging: | 0.1 ml Rabbit ascites. |
| Package Size: | 0.1 ml |
| Uses: | This antibody is useful for Western Blot, ICC, and Immunoprecipitation. |
| Application Summary: | IP, WB, ICC |
| Storage: | Aliquot and store at -20 °C. |
| General References: | 1. Nakagawara A, et al. Genomics 25(2):538-46, 1995 2. Banfield MJ, et al. Structure 9(12):1191-9, 2001 3. Minichiello L, et al. Neuron 36(1):121-37, 2002 4. Rico B, et al. Nat Neurosci 5(3):225-33, 2002 |