| Catalog Code: | NB110-62078 |
| Product Type: | Primary Antibody |
| Product Name: | VE Cadherin Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 1003 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-VE Cadherin [Tyr731] |
| Phosphorylated: | Tyr731 |
| Cross Reactivity: | This antibody is reactive against human. Chimpanzee (100% homologous), mouse, rat, chicken, zebrafish, cow, dog, and pig (91% homologous) have not been tested but are expected to react. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | VE-cadherin (cadherin-5) is an endothelial specific adhesion molecule that is essential for the maintenance of endothelial barrier function and angiogenesis. VE-cadherin is linked to the actin cytoskeleton through a number of adaptor proteins including &a |
| Alternate Names: | Anti-7B 4 antibody; Anti-7B4 antibody; Anti-7B4 antigen antibody; Anti-Cadherin 5 antibody; Anti-Cadherin 5 type 2 antibody; Anti-Cadherin5 antibody; Anti-CD 144 antibody; Anti-CD144 antibody; Anti-CD144 antigen antibody; Anti-CDH 5 antibody; Anti-CDH5 an |
| Immunogen: | The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human VE-cadherin that contains tyrosine 731. This sequence is conserved in chimpanzee. |
| Specificity: | Human. |
| Purity: | Affinity purified |
| Buffer: | Rabbit polyclonal immunoglobulin in Dulbecco's phosphate buffered saline (without Mg2+ and Ca2+), pH |
| Preservative: | 0.05% sodium azide |
| Packaging: | 0.1 ml Affinity purified Rabbit antisera. |
| Package Size: | 0.1 ml |
| Uses: | This antibody is useful in Western Blot. |
| Application Summary: | WB |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| General References: | 1. Potter, M.D., et al. (2005) Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and â-catenins and maintains the cellular mesenchymal state. J. Biol. Chem. Jul 18; [Epub ahead of print] (cites the use of this antibody). 2. Baumeis |