| Catalog Code: | NB110-62077 |
| Product Type: | Primary Antibody |
| Product Name: | VE Cadherin Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 1003 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-VE Cadherin [Tyr658] |
| Phosphorylated: | Tyr658 |
| Cross Reactivity: | Human. Mouse, rat, chicken, chimpanzee, cow, dog, and pig (100% homologous) have not yet been tested. |
| Background: | VE-cadherin (cadherin-5) is an endothelial specific adhesion molecule that is essential for the maintenance of endothelial barrier function and angiogenesis. VE-cadherin is linked to the actin cytoskeleton through a number of adaptor proteins including a- |
| Alternate Names: | Anti-7B 4 antibody; Anti-7B4 antibody; Anti-7B4 antigen antibody; Anti-Cadherin 5 antibody; Anti-Cadherin 5 type 2 antibody; Anti-Cadherin5 antibody; Anti-CD 144 antibody; Anti-CD144 antibody; Anti-CD144 antigen antibody; Anti-CDH 5 antibody; Anti-CDH5 an |
| Immunogen: | The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human VE-cadherin that contains tyrosine 658. This sequence is conserved in chicken, chimpanzee, cow, dog, mouse, pig, and rat. |
| Purity: | Affinity purified |
| Buffer: | Rabbit polyclonal immunoglobulin in Dulbecco's phosphate buffered saline (without Mg2+ and Ca2+), pH |
| Preservative: | 0.05% sodium azide |
| Packaging: | 0.1 ml Affinity purified Rabbit antisera. |
| Package Size: | 0.1 ml |
| Uses: | This antibody is useful in Western Blot |
| Application Summary: | WB |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| General References: | 1. Potter, M.D., et al. (2005) Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and â-catenins and maintains the cellular mesenchymal state. J. Biol. Chem. 280(36):31906-31912. 2. Baumeister, U., et al. (2005) Association of Csk t |