| request information: |
|
| Catalog Code: | NB110-61021 |
| Product Name: | PDGF receptor beta Antibody |
| Product Description: | Rat Monoclonal anti-PDGF receptor beta (RM0005-4C54) |
| Clone: | RM0005-4C54 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Concentration: | 0.2 mg/ml |
| Immunogen: | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse PDGF receptor-â extracellular domain. |
| Cross Reactivity: | This antibody is reactive against mouse. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Rat ascites. |
| Uses: | This antibody recognizes mouse PDGF receptor â in western blot. No crossreactivity to mouse PDGF receptor á. |
| Background: | Platelet-derived growth factors (PDGFs) exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons. |
| Storage: | Reconstitute in 0.5 ml PBS. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG2 |
| Host Name: | Rat |
| Buffer: | PBS |
| Application Summary: | immunohistochemistry 1:50-1:200, Western Blot 1:500-1:1000, |
| Species Summary: | Mu, |
| Alternate Names: | anti-CD140B antibody; anti-Beta platelet derived growth factor receptor antibody; anti-CD 140B antibody; anti-CD140b antigen antibody; anti-JTK12 antibody; anti-PDGF R beta antibody; anti-PDGFR-beta antibody; anti-PDGF R-beta antibody; anti-PDGFR antibody; anti-PDGFR1 antibody; anti-PDGFRB antibody; anti-PDGFR-B antibody; anti-PDGFR B antibody; anti-Platelet derived growth factor receptor beta antibody; anti-Platelet derived growth factor receptor beta polypeptide antibody |
| Package Size: | 0.1 mg |
| Preservative: | No Preservatives |
| Notes Main: | This antibody has been tested on frozen sections for immunohistochemistry. |
order or
more information: | company product webpage |