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| Catalog Code: | NB110-61018 |
| Product Name: | VEGFR3 Antibody |
| Product Description: | Rat Monoclonal anti-VEGFR3 (RM0003-5F63) |
| Clone: | RM0003-5F63 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Immunogen: | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse VEGFR3 extracellular domain. |
| Cross Reactivity: | This antibody is reactive against mouse. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Rat ascites. |
| Uses: | This antibody recognizes mouse VEGFR3 in western blot. No crossreactivity to mouse VEGFR1 and VEGFR2. |
| Background: | Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine esidues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, and increase vascular permeability in both large and small vessels. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. VEGF Receptor 3 is one of the five receptor tyrosine kinases (RTKs) (VEGF Receptor 1/Flt1, VEGF Receptor 2/KDR/Flk1, VEGF Receptor 3/Flt4, tie1 and tek/tie2) whose expression is almost exclusively restricted to endothelial cells. |
| Storage: | Reconstitute in 0.5 ml PBS. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG2 |
| Host Name: | Rat |
| Buffer: | PBS |
| Application Summary: | immunohistochemistry 1:50-1:200, Western Blot 1:400-1:800, |
| Species Summary: | Mu, |
| Alternate Names: | Anti-flt 4 antibody; Anti-FLT4 antibody; Anti-FLT41 antibody; Anti-fms-related tyrosine kinase 4 antibody; Anti-PCL antibody; Anti-Tyrosine protein kinase receptor FLT4 antibody; Anti-vascular endothelial growth factor receptor 3 antibody; Anti-Vascular endothelial growth factor receptor 3 precursor antibody; Anti-VEGF R3 antibody; Anti-VEGFR 3 antibody; Anti-VEGFR3 antibody; Anti-VEGFR-3 antibody; Anti-VEGF receptor3 antibody; Anti-VEGF receptor 3 antibody; Anti-VEGF receptor-3 antibody |
| Package Size: | 0.1 mg |
| Preservative: | No Preservatives |
| Notes Main: | This antibody has only been tested on frozen sections for immunohistochemistry. |
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