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| Catalog Code: | NB110-60979 |
| Product Name: | PDGF AA Antibody |
| Product Description: | Mouse Monoclonal anti-PDGF AA (MM0013-6D35) |
| Clone: | MM0013-6D35 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Immunogen: | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with human PDGF-AA recombinant protein. |
| Cross Reactivity: | This antibody is reactive against human. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | In western blots this antibody shown no cross-reactivity with E-Cadherin,and P-Cadherin. In Western blot -this antibody can detect human PDGF-AA. There is a 25% crossreactivitywith rhPDGF-AB, and no cross-reactivity with rhPDGF-BB. |
| Background: | PDGF AA is a member of the platelet derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGF AA can exist either as a homodimer or as a heterodimer with the platelet derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. |
| Storage: | Reconstitute in 0.5 ml PBS. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG2 |
| Host Name: | Mouse |
| Buffer: | PBS |
| Application Summary: | Western Blot 1:1000-1:2000, |
| Species Summary: | Hu, |
| Alternate Names: | Anti-PDGF A chain antibody; Anti-PDGF1 antibody; Anti-PDGF-A antibody; Anti-PDGF A antibody; Anti-PDGFA antibody; Anti-PDGFAA antibody; Anti-PDGF AA antibody; Anti-PDGF-AA antibody; Anti-Platelet derived growth factor A chain precursor antibody; Anti-Platelet derived growth factor alpha polypeptide antibody |
| Package Size: | 0.1 mg |
| Preservative: | No Preservatives |
| Notes Main: | This antibody has not yet been tested for immunohistochemistry. |
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more information: | company product webpage |