| CatalogCode: | NB110-60970 |
| ProductName: | PDGF receptor beta Antibody |
| Product Description: | Mouse Monoclonal anti-PDGF receptor beta (MM0005-5C37) |
| Clone: | MM0005-5C37 |
| Clonality: | Monoclonal |
| Immunogen: | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with recombinant human platelet-derived growth factor receptor alpha extracellular domain. |
| CrossReactivity: | This antibody is reactive against human. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Background: | Platelet-derived growth factors (PDGFs) exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons. |
| Storage: | Reconstitute in 0.5 ml PBS. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | PBS |
| ListPrice: | 325 |
| AppSummary: | IHC, WB |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-Beta platelet derived growth factor receptor antibody; Anti-CD 140B antibody; Anti-CD140B antibody; Anti-CD140b antigen antibody; Anti-JTK12 antibody; Anti-PDGF R beta antibody Anti-PDGFR antibody; Anti-PDGFR1 antibody; Anti-PDGFRB antibody; Anti-Platelet derived growth factor receptor beta antibody; Anti-Platelet derived growth factor receptor beta polypeptide antibody |
| PackageSize: | 0.1 mg |