| CatalogCode: | NB110-60965SS |
| ProductName: | SLC26A7 Antibody |
| Product Description: | Mouse Monoclonal anti-SLC26A7 (14H5) |
| Clone: | 14H5 |
| Clonality: | Monoclonal |
| Immunogen: | A fusion protein containing the C-terminal region of mouse SLC26A7. [Swiss-Prot# Q24JS8] |
| CrossReactivity: | Mouse. Other species have not been tested. |
| Packaging: | 0.025 ml protein G purified Mouse ascites. |
| Uses: | This antibody is useful for Western blot on cells transiently transfected with mouse SLC26A7. Previous lots have been used for immunofluorescence.Note: Do not boil the samples. |
| Background: | SLC26A7 is a Cl-/base exchanger expressed in the proximal tubule and thick ascending limb of the loop of Henle in the kidney. It is present in endosomes, and its targeting to the basolateral membrane is increased in hypertonicity and potassium depletion. The trafficking to the cell surface suggests novel functional upregulation of SLC26A7 in states that are associated with hypokalemia or increased medullary tonicity. It is thought to contribute to anion transport in the nephron segments. |
| ProductRef: | 1. Dudas, PL. et al, Am. J. Physiol. Renal Physiol. 290: 937-945 (2006) [Western blot, Immunofluorescence, Mouse] |
| Storage: | Store at 4C for short-term. Aliquot and store at -20C for long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Host_Name: | Mouse |
| Buffer: | Tris-glycine, 150mM NaCl |
| ListPrice: | 100 |
| AppSummary: | IF, WB |
| SpeciesSummary: | Mu |
| ALTnames: | anti-Solute carrier family 26 member 7 antibody |
| PackageSize: | 0.025 ml |
| Gene_Id: | 208890 |
| Omim_ID: | NB110-60965 |
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